Lineage for d1n8zc4 (1n8z C:489-607)

  1. Root: SCOP 1.65
  2. 341323Class g: Small proteins [56992] (66 folds)
  3. 341571Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (18 superfamilies)
    disulphide-bound fold; contains beta-hairpin with two adjacent disulphides
  4. 342047Superfamily g.3.9: Growth factor receptor domain [57184] (1 family) (S)
  5. 342048Family g.3.9.1: Growth factor receptor domain [57185] (5 proteins)
  6. 342061Protein Protooncoprotein Her2 extracellular domain [82889] (2 species)
  7. 342062Species Human (Homo sapiens) [TaxId:9606] [82890] (1 PDB entry)
  8. 342064Domain d1n8zc4: 1n8z C:489-607 [80325]
    Other proteins in same PDB: d1n8za1, d1n8za2, d1n8zb1, d1n8zb2, d1n8zc1, d1n8zc2
    complexed with nag, so4

Details for d1n8zc4

PDB Entry: 1n8z (more details), 2.52 Å

PDB Description: Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab

SCOP Domain Sequences for d1n8zc4:

Sequence, based on SEQRES records: (download)

>d1n8zc4 g.3.9.1 (C:489-607) Protooncoprotein Her2 extracellular domain {Human (Homo sapiens)}
chqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclpchpecqpq
ngsvtcfgpeadqcvacahykdppfcvarcpsgvkpdlsympiwkfpdeegacqpcpin

Sequence, based on observed residues (ATOM records): (download)

>d1n8zc4 g.3.9.1 (C:489-607) Protooncoprotein Her2 extracellular domain {Human (Homo sapiens)}
chqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclpchpecqpq
ngsvtcfgpeadqcvacahykdppfcvarcpsiwkfpdeegacqpcpin

SCOP Domain Coordinates for d1n8zc4:

Click to download the PDB-style file with coordinates for d1n8zc4.
(The format of our PDB-style files is described here.)

Timeline for d1n8zc4: