Lineage for d1n8zb1 (1n8z B:1-120)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 218897Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 218898Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 218899Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (15 proteins)
  6. 218958Protein Immunoglobulin (variable domains of L and H chains) [48749] (228 species)
  7. 220023Species Herceptin Fab 4D5 (synthetic, humanised version), kappa L chain [48771] (4 PDB entries)
  8. 220037Domain d1n8zb1: 1n8z B:1-120 [80320]
    Other proteins in same PDB: d1n8za2, d1n8zb2, d1n8zc1, d1n8zc2, d1n8zc3, d1n8zc4
    complexed with nag, so4

Details for d1n8zb1

PDB Entry: 1n8z (more details), 2.52 Å

PDB Description: Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab

SCOP Domain Sequences for d1n8zb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1n8zb1 b.1.1.1 (B:1-120) Immunoglobulin (variable domains of L and H chains) {Herceptin Fab 4D5 (synthetic, humanised version), kappa L chain}
evqlvesggglvqpggslrlscaasgfnikdtyihwvrqapgkglewvariyptngytry
adsvkgrftisadtskntaylqmnslraedtavyycsrwggdgfyamdywgqgtlvtvss

SCOP Domain Coordinates for d1n8zb1:

Click to download the PDB-style file with coordinates for d1n8zb1.
(The format of our PDB-style files is described here.)

Timeline for d1n8zb1: