SCOPe 2.07: Domain d1n7mh2: 1n7m H:108-213

Lineage for d1n7mh2 (1n7m H:108-213)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (151 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d1n7mh2: 1n7m H:108-213 [80253]
   Other proteins in same PDB: d1n7mh1, d1n7ml1, d1n7ml2
   part of metal chelatase catalytic Fab 7G12; germline antibody; chain identifiers are probably mixed up
   complexed with mmp

Details for d1n7mh2

PDB Entry: 1n7m, 1.8 Å

PDB Description: Germline 7G12 with N-methylmesoporphyrin

PDB Compounds: (H:) Germline Metal Chelatase Catalytic Antibody, chain H

SCOPe Domain Sequences for d1n7mh2:

Sequence; same for both SEQRES and ATOM records:

>d1n7mh2 b.1.1.2 (H:108-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge

Timeline for d1n7mh2:

• d1n7mh2 first appeared in SCOP 1.63
  
• d1n7mh2 appears in SCOPe 2.06
  
• d1n7mh2 appears in the current release, SCOPe 2.08