SCOP 1.75: Domain d1n6ka_: 1n6k A:

Lineage for d1n6ka_ (1n6k A:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (78 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rab5a [82399] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82400] (11 PDB entries)
   Uniprot P20339 18-182

8. Domain d1n6ka_: 1n6k A: [80199]
   complexed with af3, bme, gdp, mg; mutant

Details for d1n6ka_

PDB Entry: 1n6k, 1.55 Å

PDB Description: crystal structure of human rab5a a30p mutant complex with gdp and aluminum fluoride

PDB Compounds: (A:) Ras-related protein Rab-5A

SCOP Domain Sequences for d1n6ka_:

Sequence; same for both SEQRES and ATOM records:

>d1n6ka_ c.37.1.8 (A:) Rab5a {Human (Homo sapiens) [TaxId: 9606]}
gnkicqfklvllgespvgksslvlrfvkgqfhefqestigaafltqtvclddttvkfeiw
dtagqeryhslapmyyrgaqaaivvyditneesfaraknwvkelqrqaspnivialsgnk
adlankravdfqeaqsyaddnsllfmetsaktsmnvneifmaiakkl

Timeline for d1n6ka_:

• d1n6ka_ first appeared in SCOP 1.63
  
• d1n6ka_ appears in SCOP 1.73
  
• d1n6ka_ appears in SCOPe 2.01
  
• d1n6ka_ appears in the current release, SCOPe 2.08