SCOP 1.63: Domain d1n6aa2: 1n6a A:194-361

Lineage for d1n6aa2 (1n6a A:194-361)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.85: beta-clip [51268] (7 superfamilies)
   double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll

4. Superfamily b.85.7: SET domain [82199] (3 families)
   duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
   also contains a substrate-binding alpha+beta subdomain inserted in the core

5. Family b.85.7.1: Histone lysine methyltransferases [82200] (3 proteins)
   contains metal-binding preSET and postSET domains

6. Protein Histone H3 K4-specific methyltransferase SET7/9 catalytic domain [82205] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82206] (6 PDB entries)

8. Domain d1n6aa2: 1n6a A:194-361 [80122]
   Other proteins in same PDB: d1n6aa1
   complexed with mse, sam

Details for d1n6aa2

PDB Entry: 1n6a, 1.7 Å

PDB Description: Structure of SET7/9

SCOP Domain Sequences for d1n6aa2:

Sequence, based on SEQRES records:

>d1n6aa2 b.85.7.1 (A:194-361) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens)}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygydhsppgksgpeapewyqvelkafq

Sequence, based on observed residues (ATOM records):

>d1n6aa2 b.85.7.1 (A:194-361) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens)}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygypewyqvelkafq

Timeline for d1n6aa2:

• d1n6aa2 is new in SCOP 1.63
  
• d1n6aa2 appears in SCOP 1.65
  
• d1n6aa2 appears in the current release, SCOPe 2.08