Lineage for d1n3la_ (1n3l A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2105373Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
    core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
  4. 2105374Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families) (S)
  5. 2105375Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 protein domains)
    contains a conserved all-alpha subdomain at the C-terminal extension
  6. 2105558Protein Tyrosyl-tRNA synthetase (TyrRS) [52376] (6 species)
  7. 2105572Species Human (Homo sapiens) [TaxId:9606] [82355] (6 PDB entries)
  8. 2105573Domain d1n3la_: 1n3l A: [79966]
    mini-TyrRS; anticodon recognition part is more divergent; secreted cytokine with IL-8-like activity
    complexed with gol, so4

Details for d1n3la_

PDB Entry: 1n3l (more details), 1.18 Å

PDB Description: Crystal structure of a human aminoacyl-tRNA synthetase cytokine
PDB Compounds: (A:) Tyrosyl-tRNA synthetase

SCOPe Domain Sequences for d1n3la_:

Sequence, based on SEQRES records: (download)

>d1n3la_ c.26.1.1 (A:) Tyrosyl-tRNA synthetase (TyrRS) {Human (Homo sapiens) [TaxId: 9606]}
apspeeklhlitrnlqevlgeeklkeilkerelkiywgtattgkphvayfvpmskiadfl
kagcevtilfadlhayldnmkapwellelrvsyyenvikamlesigvpleklkfikgtdy
qlskeytldvyrlssvvtqhdskkagaevvkqvehpllsgllypglqaldeeylkvdaqf
ggidqrkiftfaekylpalgyskrvhlmnpmvpgltgskmssseeeskidlldrkedvkk
klkkafcepgnvenngvlsfikhvlfplksefvilrdekwggnktytayvdlekdfaaev
vhpgdlknsvevalnklldpirekfntpalkklasaayp

Sequence, based on observed residues (ATOM records): (download)

>d1n3la_ c.26.1.1 (A:) Tyrosyl-tRNA synthetase (TyrRS) {Human (Homo sapiens) [TaxId: 9606]}
apspeeklhlitrnlqevlgeeklkeilkerelkiywgtattgkphvayfvpmskiadfl
kagcevtilfadlhayldnmkapwellelrvsyyenvikamlesigvpleklkfikgtdy
qlskeytldvyrlssvvtqhdskkagaevvkqvehpllsgllypglqaldeeylkvdaqf
ggidqrkiftfaekylpalgyskrvhlmnpmvpgltgseskidlldrkedvkkklkkafc
epgnvenngvlsfikhvlfplksefvilrdekwggnktytayvdlekdfaaevvhpgdlk
nsvevalnklldpirekfntpalkklasaayp

SCOPe Domain Coordinates for d1n3la_:

Click to download the PDB-style file with coordinates for d1n3la_.
(The format of our PDB-style files is described here.)

Timeline for d1n3la_: