SCOP 1.71: Domain d1mzna_: 1mzn A:

Lineage for d1mzna_ (1mzn A:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (32 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (14 PDB entries)

8. Domain d1mzna_: 1mzn A: [79704]

Details for d1mzna_

PDB Entry: 1mzn, 1.9 Å

PDB Description: crystal structure at 1.9 angstroems resolution of the homodimer of human rxr alpha ligand binding domain bound to the synthetic agonist compound bms 649 and a coactivator peptide

SCOP Domain Sequences for d1mzna_:

Sequence, based on SEQRES records:

>d1mzna_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens)}
nedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakri
phfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaif
drvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckh
kypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records):

>d1mzna_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens)}
nedmpverileaelavepktetyveanndpvtnicqaadkqlftlvewakriphfselpl
ddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelv
skmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgr
faklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Timeline for d1mzna_:

• d1mzna_ first appeared in SCOP 1.63
  
• d1mzna_ appears in SCOP 1.69
  
• d1mzna_ appears in SCOP 1.73
  
• d1mzna_ appears in the current release, SCOPe 2.08