SCOPe 2.04: Domain d1mwsa3: 1mws A:328-668

Lineage for d1mwsa3 (1mws A:328-668)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)

6. Protein Penicillin binding protein 2a (PBP2A), C-terminal domain [82838] (1 species)

7. Species Staphylococcus aureus [TaxId:1280] [82839] (6 PDB entries)
   Uniprot O54286 27-668

8. Domain d1mwsa3: 1mws A:328-668 [79594]
   Other proteins in same PDB: d1mwsa1, d1mwsa2, d1mwsb1, d1mwsb2
   complexed with cd, cl

Details for d1mwsa3

PDB Entry: 1mws, 2 Å

PDB Description: Structure of nitrocefin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.00 A resolution.

PDB Compounds: (A:) penicillin-binding protein 2a

SCOPe Domain Sequences for d1mwsa3:

Sequence, based on SEQRES records:

>d1mwsa3 e.3.1.1 (A:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
idakvqksiynnmkndygsgtaihpqtgellalvstpsydvypfmygmsneeynkltedk
kepllnkfqittspgstqkiltamiglnnktlddktsykidgkgwqkdkswggynvtrye
vvngnidlkqaiessdniffarvalelgskkfekgmkklgvgedipsdypfynaqisnkn
ldneilladsgygqgeilinpvqilsiysalenngninaphllkdtknkvwkkniisken
inlltdgmqqvvnkthkediyrsyanligksgtaelkmkqgetgrqigwfisydkdnpnm
mmainvkdvqdkgmasynakisgkvydelyengnkkydide

Sequence, based on observed residues (ATOM records):

>d1mwsa3 e.3.1.1 (A:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
idakvqksiynnmkndygsgtaihpqtgellalvstpsydvypfmygmsneeynkltedk
kepllnkfqittspgstqkiltamiglnnktlddktsykidgkgwqkdkswggynvtrye
vvngnidlkqaiessdniffarvalelgskkfekgmkklgvgedipsdypfynaqisnkn
ldneilladsgygqgeilinpvqilsiysalenngninaphllkdtknkvwkkniisken
inlltdgmqqvvnkthkediyrsyanligksgtaelkqigwfisydkdnpnmmmainvkd
vqdkgmasynakisgkvydelyengnkkydide

Timeline for d1mwsa3:

• d1mwsa3 first appeared in SCOP 1.63
  
• d1mwsa3 appears in SCOPe 2.03
  
• d1mwsa3 appears in SCOPe 2.05
  
• d1mwsa3 appears in the current release, SCOPe 2.08