Lineage for d1mt7b_ (1mt7 B:)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 231370Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 231371Superfamily b.50.1: Acid proteases [50630] (2 families) (S)
  5. 231372Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 231388Protein Human immunodeficiency virus type 1 protease [50632] (1 species)
  7. 231389Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (151 PDB entries)
  8. 231473Domain d1mt7b_: 1mt7 B: [79449]
    complexed with act; mutant

Details for d1mt7b_

PDB Entry: 1mt7 (more details), 1.9 Å

PDB Description: viability of a drug-resistant hiv-1 protease mutant: structural insights for better antiviral therapy

SCOP Domain Sequences for d1mt7b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1mt7b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwkrplvtiriggqlkeallntgaddtvleemnlpgkwkpkmiggiggfikvrqyd
qipveicghkaigtvlvgptpaniigrnlltqigctlnf

SCOP Domain Coordinates for d1mt7b_:

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Timeline for d1mt7b_: