Lineage for d1mt7b_ (1mt7 B:)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (578 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. Domain d1mt7b_: 1mt7 B: [79449]
    complexed with act; mutant

Details for d1mt7b_

PDB Entry: 1mt7 (more details), 1.9 Å

PDB Description: viability of a drug-resistant hiv-1 protease mutant: structural insights for better antiviral therapy
PDB Compounds: (B:) protease retropepsin

SCOPe Domain Sequences for d1mt7b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1mt7b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtiriggqlkeallntgaddtvleemnlpgkwkpkmiggiggfikvrqyd
qipveicghkaigtvlvgptpaniigrnlltqigctlnf

SCOPe Domain Coordinates for d1mt7b_ are not available.

Timeline for d1mt7b_:

View in 3D
Domains from other chains:
(mouse over for more information)
d1mt7a_