SCOP 1.71: Domain d1mswd_: 1msw D:

Lineage for d1mswd_ (1msw D:)

1. Root: SCOP 1.71

2. Class e: Multi-domain proteins (alpha and beta) [56572] (48 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.3: T7 RNA polymerase [56691] (1 protein)

6. Protein T7 RNA polymerase [56692] (1 species)
   multidomain; mostly alpha

7. Species Bacteriophage T7 [TaxId:10760] [56693] (9 PDB entries)

8. Domain d1mswd_: 1msw D: [79427]
   elongation complex; shows dramatic conformational changes in the transition from initiation to elongation transcription

Details for d1mswd_

PDB Entry: 1msw, 2.1 Å

PDB Description: Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase

SCOP Domain Sequences for d1mswd_:

Sequence, based on SEQRES records:

>d1mswd_ e.8.1.3 (D:) T7 RNA polymerase {Bacteriophage T7}
ntiniakndfsdielaaipfntladhygerlareqlalehesyemgearfrkmferqlka
gevadnaaakplittllpkmiarindwfeevkakrgkrptafqflqeikpeavayitikt
tlacltsadnttvqavasaigraiedearfgrirdleakhfkknveeqlnkrvghvykka
fmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhrqnagvvgqds
etielapeyaeaiatragalagispmfqpcvvppkpwtgitgggywangrrplalvrths
kkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelp
mkpedidmnpealtawkraaaavyrkdkarksrrislefmleqankfanhkaiwfpynmd
wrgrvyavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikf
ieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscs
giqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtden
tgeisekvklgtkalagqwlaygvtrsvtkrsvmtlaygskefgfrqqvledtiqpaids
gkglmftqpnqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrk
rcavhwvtpdgfpvwqeykkpiqtrlnlmflgqfrlqptintnkdseidahkqesgiapn
fvhsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdv
ladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa

Sequence, based on observed residues (ATOM records):

>d1mswd_ e.8.1.3 (D:) T7 RNA polymerase {Bacteriophage T7}
ntiniakndfsdielaaipfntladhygerlareqlalehesyemgearfrkmferqlka
gevadnaaakplittllpkmiarindwfeevkakrgkrptafqflqeikpeavayitikt
tlacltsadnttvqavasaigraiedearfgrirdleakhfkknveeqlnkrvghvykka
fmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhrqsetielape
yaeaiatragalagispmfqpcvvppkpwtgitgggywangrrplalvrthskkalmrye
dvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmktawkra
aaavyrkdkarksrrislefmleqankfanhkaiwfpynmdwrgrvyavsmfnpqgndmt
kglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplent
wwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravn
llpsetvqdiygivakkvneilqadaingtdnevvtvtdentgeisekvklgtkalagqw
laygvtrsvtkrsvmtlaygskefgfrqqvledtiqpaidsgkglmftqpnqaagymakl
iwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeyk
kpiqtrlnlmflgqfrlqptintnkdseidahkqesgiapnfvhsqdgshlrktvvwahe
kygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldk
mpalpakgnlnlrdilesdfafa

Timeline for d1mswd_:

• d1mswd_ first appeared in SCOP 1.63
  
• d1mswd_ appears in SCOP 1.69
  
• d1mswd_ appears in SCOP 1.73
  
• d1mswd_ appears in the current release, SCOPe 2.08