SCOPe 2.08: Domain d1mr1c1: 1mr1 C:219-312

Lineage for d1mr1c1 (1mr1 C:219-312)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.217: SAND domain-like [63762] (1 superfamily)
   core: three short helices packed against a barrel-like beta-sheet; some similarity to the SH3-like fold

4. Superfamily d.217.1: SAND domain-like [63763] (2 families)

5. Family d.217.1.2: SMAD4-binding domain of oncoprotein Ski [82611] (1 protein)
   automatically mapped to Pfam PF08782

6. Protein SMAD4-binding domain of oncoprotein Ski [82612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82613] (1 PDB entry)

8. Domain d1mr1c1: 1mr1 C:219-312 [79420]
   Other proteins in same PDB: d1mr1a_, d1mr1b_, d1mr1c2, d1mr1d2
   complex with SMAD4 domain
   complexed with zn

Details for d1mr1c1

PDB Entry: 1mr1, 2.85 Å

PDB Description: Crystal Structure of a Smad4-Ski Complex

PDB Compounds: (C:) Ski oncogene

SCOPe Domain Sequences for d1mr1c1:

Sequence; same for both SEQRES and ATOM records:

>d1mr1c1 d.217.1.2 (C:219-312) SMAD4-binding domain of oncoprotein Ski {Human (Homo sapiens) [TaxId: 9606]}
rvyhecfgkckgllvpelysspsaaciqcldcrlmypphkfvvhshkalenrtchwgfds
anwrayillsqdytgkeeqarlgrclddvkekfd

Timeline for d1mr1c1:

• d1mr1c1 first appeared in SCOP 1.63, called d1mr1c_
  
• d1mr1c1 appears in SCOPe 2.07