Lineage for d1mr1a_ (1mr1 A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2042020Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
    sandwich; 11 strands in 2 sheets; greek-key
  4. 2042021Superfamily b.26.1: SMAD/FHA domain [49879] (5 families) (S)
    has a few short helices inserted in loops
  5. 2042022Family b.26.1.1: SMAD domain [49880] (5 protein domains)
  6. 2042042Protein Smad4 tumor suppressor C-terminal domain [49881] (1 species)
  7. 2042043Species Human (Homo sapiens) [TaxId:9606] [49882] (6 PDB entries)
    Uniprot Q13485 314-546
  8. 2042053Domain d1mr1a_: 1mr1 A: [79418]
    Other proteins in same PDB: d1mr1c1, d1mr1c2, d1mr1d1, d1mr1d2
    complex with Ski
    complexed with zn

Details for d1mr1a_

PDB Entry: 1mr1 (more details), 2.85 Å

PDB Description: Crystal Structure of a Smad4-Ski Complex
PDB Compounds: (A:) Mothers against decapentaplegic homolog 4

SCOPe Domain Sequences for d1mr1a_:

Sequence, based on SEQRES records: (download)

>d1mr1a_ b.26.1.1 (A:) Smad4 tumor suppressor C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
apeywcsiayfemdvqvgetfkvpsscpivtvdgyvdpsggdrfclgqlsnvhrteaier
arlhigkgvqleckgegdvwvrclsdhavfvqsyyldreagrapgdavhkiypsayikvf
dlrqchrqmqqqaataqaaaaaqaaavagnipgpgsvggiapaislsaaagigvddlrrl
cilrmsfvkgwgpdyprqsiketpcwieihlhralqlldevlhtm

Sequence, based on observed residues (ATOM records): (download)

>d1mr1a_ b.26.1.1 (A:) Smad4 tumor suppressor C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
apeywcsiayfemdvqvgetfkvpsscpivtvdgyvdpsggdrfclgqlsnvhrteaier
arlhigkgvqleckgegdvwvrclsdhavfvqsyyldreagrapgdavhkiypsayikvf
dlrqchrqmqqqaataqaaaaaqvddlrrlcilrmsfvkgwgpdyprqsiketpcwieih
lhralqlldevlhtm

SCOPe Domain Coordinates for d1mr1a_:

Click to download the PDB-style file with coordinates for d1mr1a_.
(The format of our PDB-style files is described here.)

Timeline for d1mr1a_: