SCOPe 2.08: Domain d1ml9a_: 1ml9 A:

Lineage for d1ml9a_ (1ml9 A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.85: beta-clip [51268] (7 superfamilies)
   double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll

4. Superfamily b.85.7: SET domain [82199] (4 families)
   duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
   also contains a substrate-binding alpha+beta subdomain inserted in the core
   Pfam PF00856

5. Family b.85.7.1: Histone lysine methyltransferases [82200] (3 proteins)
   contains metal-binding preSET (Pfam PF05033) or AWS (Associated With SET, Pfam PF17907), and postSET domains

6. Protein Dim-5 [82201] (1 species)

7. Species Fungus (Neurospora crassa) [TaxId:5141] [82202] (2 PDB entries)

8. Domain d1ml9a_: 1ml9 A: [79282]
   complexed with unk, zn
   has additional insertions and/or extensions that are not grouped together

Details for d1ml9a_

PDB Entry: 1ml9, 1.98 Å

PDB Description: Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase

PDB Compounds: (A:) Histone H3 methyltransferase DIM-5

SCOPe Domain Sequences for d1ml9a_:

Sequence, based on SEQRES records:

>d1ml9a_ b.85.7.1 (A:) Dim-5 {Fungus (Neurospora crassa) [TaxId: 5141]}
qlpisivnreddaflnpnfrfidhsiigknvpvadqsfrvgcscasdeecmystcqclde
mapdsdeeadpytrkkrfayysqgakkgllrdrvlqsqepiyechqgcacskdcpnrvve
rgrtvplqifrtkdrgwgvkcpvnikrgqfvdrylgeiitseeadrrraestiarrkdvy
lfaldkfsdpdsldpllagqplevdgeymsgptrfinhscdpnmaifarvgdhadkhihd
lalfaikdipkgteltfdyvngltglesdahdpskisemtkclc

Sequence, based on observed residues (ATOM records):

>d1ml9a_ b.85.7.1 (A:) Dim-5 {Fungus (Neurospora crassa) [TaxId: 5141]}
qlpisivnreddaflnpnfrfidhsiigknvpvadqsfrvgcscasdeecmystcqclde
mapdkrfayysqgakkgllrdrvlqsqepiyechqgcacskdcpnrvvergrtvplqifr
tkdrgwgvkcpvnikrgqfvdrylgeiitseeadrrraestiarrkdvylfaldkfsdpd
sldpllagqplevdgeymsgptrfinhscdpnmaifarvgdhadkhihdlalfaikdipk
gteltfdyvnkisemtkclc

Timeline for d1ml9a_:

• d1ml9a_ first appeared in SCOP 1.63
  
• d1ml9a_ appears in SCOPe 2.07