SCOPe 2.03: Domain d1mk2a_: 1mk2 A:

Lineage for d1mk2a_ (1mk2 A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
   sandwich; 11 strands in 2 sheets; greek-key

4. Superfamily b.26.1: SMAD/FHA domain [49879] (5 families)
   has a few short helices inserted in loops

5. Family b.26.1.1: SMAD domain [49880] (4 proteins)

6. Protein Smad3 MH2 domain [82030] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82031] (3 PDB entries)
   Uniprot P84022 228-425

8. Domain d1mk2a_: 1mk2 A: [79217]
   Other proteins in same PDB: d1mk2b_
   complexed with acy

Details for d1mk2a_

PDB Entry: 1mk2, 2.74 Å

PDB Description: SMAD3 SBD complex

PDB Compounds: (A:) smad 3

SCOPe Domain Sequences for d1mk2a_:

Sequence; same for both SEQRES and ATOM records:

>d1mk2a_ b.26.1.1 (A:) Smad3 MH2 domain {Human (Homo sapiens) [TaxId: 9606]}
dlqpvtycepafwcsisyyelnqrvgetfhasqpsmtvdgftdpsnserfclgllsnvnr
naaveltrrhigrgvrlyyiggevfaeclsdsaifvqspncnqrygwhpatvckippgcn
lkifnnqefaallaqsvnqgfeavyqltrmctirmsfvkgwgaeyrrqtvtstpcwielh
lngplqwldkvltqmgs

Timeline for d1mk2a_:

• d1mk2a_ first appeared in SCOP 1.63
  
• d1mk2a_ appears in SCOPe 2.02
  
• d1mk2a_ appears in SCOPe 2.04
  
• d1mk2a_ appears in the current release, SCOPe 2.08