SCOP 1.73: Domain d1mh0b_: 1mh0 B:

Lineage for d1mh0b_ (1mh0 B:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (163 PDB entries)

8. Domain d1mh0b_: 1mh0 B: [79111]
   anticoagulant slow form
   complexed with nag; mutant

Details for d1mh0b_

PDB Entry: 1mh0, 2.8 Å

PDB Description: crystal structure of the anticoagulant slow form of thrombin

PDB Compounds: (B:) Prothrombin

SCOP Domain Sequences for d1mh0b_:

Sequence, based on SEQRES records:

>d1mh0b_ b.47.1.2 (B:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
adcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Sequence, based on observed residues (ATOM records):

>d1mh0b_ b.47.1.2 (B:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
adcglrplfekksledkterellesyiivegsdaeigmspwqvmlfrkspqellcgasli
sdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihprynwr
enldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketgqpsvl
qvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwy
qmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Timeline for d1mh0b_:

• d1mh0b_ first appeared in SCOP 1.63
  
• d1mh0b_ appears in SCOP 1.71
  
• d1mh0b_ appears in SCOP 1.75
  
• d1mh0b_ appears in the current release, SCOPe 2.08