SCOPe 2.06: Domain d1mf8c_: 1mf8 C:

Lineage for d1mf8c_ (1mf8 C:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.62: Cyclophilin-like [50890] (1 superfamily)
   barrel, closed; n=8, S=10; complex topology

4. Superfamily b.62.1: Cyclophilin-like [50891] (5 families)

5. Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (13 proteins)
   automatically mapped to Pfam PF00160

6. Protein Cyclophilin (eukaryotic) [50893] (13 species)

7. Species Human (Homo sapiens), variant A [TaxId:9606] [50894] (113 PDB entries)
   Uniprot P05092

8. Domain d1mf8c_: 1mf8 C: [79042]
   Other proteins in same PDB: d1mf8a_, d1mf8b_
   complexed with ca, po4

Details for d1mf8c_

PDB Entry: 1mf8, 3.1 Å

PDB Description: Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin

PDB Compounds: (C:) Peptidyl-prolyl cis-trans isomerase A

SCOPe Domain Sequences for d1mf8c_:

Sequence; same for both SEQRES and ATOM records:

>d1mf8c_ b.62.1.1 (C:) Cyclophilin (eukaryotic) {Human (Homo sapiens), variant A [TaxId: 9606]}
mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgql

Timeline for d1mf8c_:

• d1mf8c_ first appeared in SCOP 1.63
  
• d1mf8c_ appears in SCOPe 2.05
  
• d1mf8c_ appears in the current release, SCOPe 2.07