SCOP 1.71: Domain d1mf8c_: 1mf8 C:

Lineage for d1mf8c_ (1mf8 C:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.62: Cyclophilin-like [50890] (1 superfamily)
   barrel, closed; n=8, S=10; complex topology

4. Superfamily b.62.1: Cyclophilin-like [50891] (2 families)

5. Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (3 proteins)

6. Protein Cyclophilin (eukaryotic) [50893] (10 species)

7. Species Human (Homo sapiens), variant A [TaxId:9606] [50894] (45 PDB entries)

8. Domain d1mf8c_: 1mf8 C: [79042]
   Other proteins in same PDB: d1mf8a_, d1mf8b_
   complexed with aba, bmt, ca, dal, mle, mva, po4, sar

Details for d1mf8c_

PDB Entry: 1mf8, 3.1 Å

PDB Description: Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin

SCOP Domain Sequences for d1mf8c_:

Sequence; same for both SEQRES and ATOM records:

>d1mf8c_ b.62.1.1 (C:) Cyclophilin (eukaryotic) {Human (Homo sapiens), variant A}
mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgql

Timeline for d1mf8c_:

• d1mf8c_ first appeared in SCOP 1.63
  
• d1mf8c_ appears in SCOP 1.69
  
• d1mf8c_ appears in SCOP 1.73
  
• d1mf8c_ appears in the current release, SCOPe 2.08