SCOP 1.69: Domain d1mc8a1: 1mc8 A:221-332

Lineage for d1mc8a1 (1mc8 A:221-332)

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.60: SAM domain-like [47768] (13 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.7: 5' to 3' exonuclease, C-terminal subdomain [47807] (1 family)

5. Family a.60.7.1: 5' to 3' exonuclease, C-terminal subdomain [47808] (4 proteins)

6. Protein Flap endonuclease-1 (Fen-1 nuclease) [47815] (4 species)

7. Species Archaeon Pyrococcus horikoshii [TaxId:53953] [81798] (1 PDB entry)

8. Domain d1mc8a1: 1mc8 A:221-332 [78945]
   Other proteins in same PDB: d1mc8a2, d1mc8b2

Details for d1mc8a1

PDB Entry: 1mc8, 3.1 Å

PDB Description: crystal structure of flap endonuclease-1 r42e mutant from pyrococcus horikoshii

SCOP Domain Sequences for d1mc8a1:

Sequence; same for both SEQRES and ATOM records:

>d1mc8a1 a.60.7.1 (A:221-332) Flap endonuclease-1 (Fen-1 nuclease) {Archaeon Pyrococcus horikoshii}
itreklielailvgtdynpggvkgigpkkaleivrysrdplakfqrqsdvdlyaikeffl
nppvtneyslswkepdeegilkflcdehnfseervkngierlkkaikagrqs

Timeline for d1mc8a1:

• d1mc8a1 first appeared in SCOP 1.63
  
• d1mc8a1 appears in SCOP 1.67
  
• d1mc8a1 appears in SCOP 1.71
  
• d1mc8a1 appears in the current release, SCOPe 2.08