SCOPe 2.08: Domain d1mc1a2: 1mc1 A:5-209

Lineage for d1mc1a2 (1mc1 A:5-209)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.1: Class II glutamine amidotransferases [56236] (6 proteins)
   has slightly different topology than other families do

6. Protein beta-Lactam synthetase [69831] (2 species)
   Asparagine synthetase B homologue

7. Species Streptomyces clavuligerus [TaxId:1901] [69832] (5 PDB entries)

8. Domain d1mc1a2: 1mc1 A:5-209 [78940]
   Other proteins in same PDB: d1mc1a1, d1mc1b1
   complexed with amp, mg, pcx, pop

Details for d1mc1a2

PDB Entry: 1mc1, 2.16 Å

PDB Description: beta-lactam synthetase with product (dgpc), amp and ppi

PDB Compounds: (A:) beta-lactam synthetase

SCOPe Domain Sequences for d1mc1a2:

Sequence, based on SEQRES records:

>d1mc1a2 d.153.1.1 (A:5-209) beta-Lactam synthetase {Streptomyces clavuligerus [TaxId: 1901]}
vlpaafgflasartgggrapgpvfatrgshtdidtpqgerslaatlvhapsvapdravar
sltgapttavlageiynrdellsvlpagpapegdaelvlrllerydlhafrlvngrfatv
vrtgdrvllatdhagsvplytcvapgevrasteakalaahrdpkgfpladarrvagltgv
yqvpagavmdidlgsgtavthrtwt

Sequence, based on observed residues (ATOM records):

>d1mc1a2 d.153.1.1 (A:5-209) beta-Lactam synthetase {Streptomyces clavuligerus [TaxId: 1901]}
vlpaafgflasargpvfatrgshtdidtpqgerslaatlvhapsvapdravarsltgapt
tavlageiynrdellsvlpagpapegdaelvlrllerydlhafrlvngrfatvvrtgdrv
llatdhagsvplytcvapgevrasteakalaagfpladarrvagltgvyqvpagavmdid
lgsgtavthrtwt

Timeline for d1mc1a2:

• d1mc1a2 first appeared in SCOP 1.63
  
• d1mc1a2 appears in SCOPe 2.07