SCOP 1.67: Domain d1mbza2: 1mbz A:3-209

Lineage for d1mbza2 (1mbz A:3-209)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (5 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.1: Class II glutamine amidotransferases [56236] (5 proteins)
   has slightly different topology than other families do

6. Protein beta-Lactam synthetase [69831] (2 species)
   Asparagine synthetase B homologue

7. Species Streptomyces clavuligerus [TaxId:1901] [69832] (5 PDB entries)

8. Domain d1mbza2: 1mbz A:3-209 [78934]
   Other proteins in same PDB: d1mbza1, d1mbzb1

Details for d1mbza2

PDB Entry: 1mbz, 2.47 Å

PDB Description: beta-lactam synthetase with trapped intermediate

SCOP Domain Sequences for d1mbza2:

Sequence, based on SEQRES records:

>d1mbza2 d.153.1.1 (A:3-209) beta-Lactam synthetase {Streptomyces clavuligerus}
apvlpaafgflasartgggrapgpvfatrgshtdidtpqgerslaatlvhapsvapdrav
arsltgapttavlageiynrdellsvlpagpapegdaelvlrllerydlhafrlvngrfa
tvvrtgdrvllatdhagsvplytcvapgevrasteakalaahrdpkgfpladarrvaglt
gvyqvpagavmdidlgsgtavthrtwt

Sequence, based on observed residues (ATOM records):

>d1mbza2 d.153.1.1 (A:3-209) beta-Lactam synthetase {Streptomyces clavuligerus}
apvlpaafgflasartggpvfatrgshtdidtpqgerslaatlvhapsvapdravarslt
gapttavlageiynrdellsvlpagpapegdaelvlrllerydlhafrlvngrfatvvrt
gdrvllatdhagsvplytcvapgevrasteakalaahgfpladarrvagltgvyqvpaga
vmdidlgsgtavthrtwt

Timeline for d1mbza2:

• d1mbza2 first appeared in SCOP 1.63
  
• d1mbza2 appears in SCOP 1.65
  
• d1mbza2 appears in SCOP 1.69
  
• d1mbza2 appears in the current release, SCOPe 2.08