SCOPe 2.05: Domain d1m66a1: 1m66 A:198-357

Lineage for d1m66a1 (1m66 A:198-357)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

4. Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

5. Family a.100.1.6: Glycerol-3-phosphate dehydrogenase [48197] (1 protein)
   automatically mapped to Pfam PF07479

6. Protein Glycerol-3-phosphate dehydrogenase [48198] (2 species)

7. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [48199] (7 PDB entries)
   Uniprot O29390

8. Domain d1m66a1: 1m66 A:198-357 [78689]
   Other proteins in same PDB: d1m66a2
   complexed with bcp, plm

Details for d1m66a1

PDB Entry: 1m66, 1.9 Å

PDB Description: Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine

PDB Compounds: (A:) glycerol-3-phosphate dehydrogenase

SCOPe Domain Sequences for d1m66a1:

Sequence, based on SEQRES records:

>d1m66a1 a.100.1.6 (A:198-357) Glycerol-3-phosphate dehydrogenase {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
tdtvgcevasavknvlaigsgvanglgmglnaraalimrglleirdltaalggdgsavfg
laglgdlqltcsselsrnftvgkklgkglpieeiqrtskavaegvatadplmrlakqlkv
kmplchqiyeivykkknprdaladllscglqdeglpplfk

Sequence, based on observed residues (ATOM records):

>d1m66a1 a.100.1.6 (A:198-357) Glycerol-3-phosphate dehydrogenase {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
tdtvgcevasavknvlaigsgvanglgmglnaraalimrglleirdltaalggdgsavfg
laglgdlqltcsselsrnftvgkklgkglpieeiqravaegvatadplmrlakqlkvkmp
lchqiyeivykkknprdaladllscglqdeglpplfk

Timeline for d1m66a1:

• d1m66a1 first appeared in SCOP 1.63
  
• d1m66a1 appears in SCOPe 2.04
  
• d1m66a1 appears in SCOPe 2.06
  
• d1m66a1 appears in the current release, SCOPe 2.08