SCOPe 2.08: Domain d1m5ns_: 1m5n S:

Lineage for d1m5ns_ (1m5n S:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (28 families)

5. Family a.118.1.1: Armadillo repeat [48372] (7 proteins)
   this is a repeat family; one repeat unit is 1ee4 A:288-330 found in domain

6. Protein Importin beta [48378] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48379] (11 PDB entries)

8. Domain d1m5ns_: 1m5n S: [78653]
   bound to the non-classical nls(67-94) of pthrp, chain Q
   applies to all domains of a family if the common domain is composed of a different number of small repeating units

Details for d1m5ns_

PDB Entry: 1m5n, 2.9 Å

PDB Description: Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP

PDB Compounds: (S:) importin beta-1 subunit

SCOPe Domain Sequences for d1m5ns_:

Sequence; same for both SEQRES and ATOM records:

>d1m5ns_ a.118.1.1 (S:) Importin beta {Human (Homo sapiens) [TaxId: 9606]}
melitilektvspdrleleaaqkfleraavenlptflvelsrvlanpgnsqvarvaaglq
iknsltskdpdikaqyqqrwlaidanarrevknyvlqtlgtetyrpssasqcvagiacae
ipvnqwpelipqlvanvtnpnstehmkestleaigyicqdidpeqlqdksneiltaiiqg
mrkeepsnnvklaatnallnsleftkanfdkeserhfimqvvceatqcpdtrvrvaalqn
lvkimslyyqymetymgpalfaitieamksdidevalqgiefwsnvcdeemdlaieasea
aeqgrppehtskfyakgalqylvpiltqtltkqdendddddwnpckaagvclmllatcce
ddivphvlpfikehiknpdwryrdaavmafgcilegpepsqlkplviqamptlielmkdp
svvvrdtaawtvgricellpeaaindvylapllqclieglsaeprvasnvcwafsslaea
ayeaa

Timeline for d1m5ns_:

• d1m5ns_ first appeared in SCOP 1.63
  
• d1m5ns_ appears in SCOPe 2.07