SCOPe 2.06: Domain d1m4ua_: 1m4u A:

Lineage for d1m4ua_ (1m4u A:)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.7: Noggin [82904] (1 protein)
   automatically mapped to Pfam PF05806

6. Protein Noggin [82905] (1 species)
   BMP-7 antagonist

7. Species Human (Homo sapiens) [TaxId:9606] [82906] (1 PDB entry)

8. Domain d1m4ua_: 1m4u A: [78625]
   Other proteins in same PDB: d1m4ul_

Details for d1m4ua_

PDB Entry: 1m4u, 2.42 Å

PDB Description: crystal structure of bone morphogenetic protein-7 (bmp-7) in complex with the secreted antagonist noggin

PDB Compounds: (A:) Noggin

SCOPe Domain Sequences for d1m4ua_:

Sequence, based on SEQRES records:

>d1m4ua_ g.17.1.7 (A:) Noggin {Human (Homo sapiens) [TaxId: 9606]}
mqhylhirpapsdnlplvdliehpdpifdpkekdlnetllrsllgghydpgfmatspped
rpgggggaaggaedlaeldqllrqrpsgampseikglefseglaqgkkqrlskklrrklq
mwlwsqtfcpvlyawndlgsrfwpryvkvgscfskrscsvpegmvckpsksvhltvlrwr
cqrrggqrcgwipiqypiiseckcsc

Sequence, based on observed residues (ATOM records):

>d1m4ua_ g.17.1.7 (A:) Noggin {Human (Homo sapiens) [TaxId: 9606]}
mqhylhirpapsdnlplvdliehpdpifdpkekdlnetllrsllgghydpgfmatspped
rpggaedlaeldqllrqrpsgampseikglefseglaqgkkqrlskklrrklqmwlwsqt
fcpvlyawndlgsrfwpryvkvgscfskrscsvpegmvckpsksvhltvlrwrcqrrggq
rcgwipiqypiiseckcsc

Timeline for d1m4ua_:

• d1m4ua_ first appeared in SCOP 1.63
  
• d1m4ua_ appears in SCOPe 2.05
  
• d1m4ua_ appears in SCOPe 2.07
  
• d1m4ua_ appears in the current release, SCOPe 2.08, called d1m4ua1