SCOP 1.71: Domain d1lwta3: 1lwt A:299-415

Lineage for d1lwta3 (1lwt A:299-415)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.95: Homing endonuclease-like [55603] (2 superfamilies)
   alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

4. Superfamily d.95.2: Homing endonucleases [55608] (2 families)

5. Family d.95.2.2: Intein endonuclease [55614] (2 proteins)
   duplication: contains tandem repeat of this fold

6. Protein VMA1-derived endonuclease (VDE) PI-SceI [55615] (1 species)
   homing endonuclease with protein splicing activity

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55616] (7 PDB entries)

8. Domain d1lwta3: 1lwt A:299-415 [78280]
   Other proteins in same PDB: d1lwta1
   complexed with mse

Details for d1lwta3

PDB Entry: 1lwt, 3.2 Å

PDB Description: Crystal structure of the intein homing endonuclease PI-SceI bound to its substrate DNA (Ca2+ free)

SCOP Domain Sequences for d1lwta3:

Sequence; same for both SEQRES and ATOM records:

>d1lwta3 d.95.2.2 (A:299-415) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae)}
gvknipsflstdnigtretflaglidsdgyvtdehgikatiktihtsvrdglvslarslg
lvvsvnaepakvdmngtkhkisyaiymsggdvllnvlskcagskkfrpapaaafare

Timeline for d1lwta3:

• d1lwta3 first appeared in SCOP 1.63
  
• d1lwta3 appears in SCOP 1.69
  
• d1lwta3 appears in SCOP 1.73
  
• d1lwta3 appears in the current release, SCOPe 2.08