Lineage for d1lw2a2 (1lw2 A:1-429)

  1. Root: SCOP 1.65
  2. 338536Class e: Multi-domain proteins (alpha and beta) [56572] (38 folds)
  3. 339256Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 339257Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 339321Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)
  6. 339322Protein HIV-1 reverse transcriptase [56689] (2 species)
  7. 339323Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (63 PDB entries)
  8. 339393Domain d1lw2a2: 1lw2 A:1-429 [78252]
    Other proteins in same PDB: d1lw2a1
    complexed with csd, po4, u05; mutant

Details for d1lw2a2

PDB Entry: 1lw2 (more details), 3 Å

PDB Description: crystal structure of t215y mutant hiv-1 reverse transcriptase in complex with 1051u91
PDB Compounds: (A:)

SCOP Domain Sequences for d1lw2a2:

Sequence, based on SEQRES records: (download)

>d1lw2a2 e.8.1.2 (A:1-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglytpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlakllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyql

Sequence, based on observed residues (ATOM records): (download)

>d1lw2a2 e.8.1.2 (A:1-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
farklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrwglytpdkkhqkeppflwmgyelhpdkwtvqpivlpek
dswtvndiqklvgklnwasqiypgikvrqlakllrgtkalteviplteeaelelaenrei
lkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlt
eavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql

SCOP Domain Coordinates for d1lw2a2:

Click to download the PDB-style file with coordinates for d1lw2a2.
(The format of our PDB-style files is described here.)

Timeline for d1lw2a2:

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Domains from same chain:
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d1lw2a1
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Domains from other chains:
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d1lw2b_