Lineage for d1lw0a1 (1lw0 A:430-537)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2122050Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 2123751Superfamily c.55.3: Ribonuclease H-like [53098] (15 families) (S)
    consists of one domain of this fold
  5. 2123752Family c.55.3.1: Ribonuclease H [53099] (5 protein domains)
  6. 2123803Protein HIV RNase H (Domain of reverse transcriptase) [53105] (3 species)
  7. 2123813Species Human immunodeficiency virus type 1 [TaxId:11676] [53106] (104 PDB entries)
    Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
  8. 2123864Domain d1lw0a1: 1lw0 A:430-537 [78248]
    Other proteins in same PDB: d1lw0a2, d1lw0b_
    complexed with nvp, po4; mutant

Details for d1lw0a1

PDB Entry: 1lw0 (more details), 2.8 Å

PDB Description: crystal structure of t215y mutant hiv-1 reverse transcriptase in complex with nevirapine
PDB Compounds: (A:) hiv-1 reverse transcriptase

SCOPe Domain Sequences for d1lw0a1:

Sequence, based on SEQRES records: (download)

>d1lw0a1 c.55.3.1 (A:430-537) HIV RNase H (Domain of reverse transcriptase) {Human immunodeficiency virus type 1 [TaxId: 11676]}
ekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiylalqds
glevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvp

Sequence, based on observed residues (ATOM records): (download)

>d1lw0a1 c.55.3.1 (A:430-537) HIV RNase H (Domain of reverse transcriptase) {Human immunodeficiency virus type 1 [TaxId: 11676]}
ekepivgaetfyvdagyvtnrgrqkvvtltdttnqktelqaiylalqdsglevnivtdsq
yalgiiqaqpdqseselvnqiieqlikkekvylawvp

SCOPe Domain Coordinates for d1lw0a1:

Click to download the PDB-style file with coordinates for d1lw0a1.
(The format of our PDB-style files is described here.)

Timeline for d1lw0a1:

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Domains from same chain:
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d1lw0a2
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Domains from other chains:
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d1lw0b_