Lineage for d1lixa2 (1lix A:57-159,A:262-439)

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 235645Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 237513Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (6 families) (S)
  5. 237514Family c.1.12.1: Pyruvate kinase [51622] (1 protein)
  6. 237515Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
    this domain is interrupted by an all-beta domain
    C-terminal domain is alpha/beta
  7. 237536Species Human (Homo sapiens) [TaxId:9606] [82273] (4 PDB entries)
  8. 237549Domain d1lixa2: 1lix A:57-159,A:262-439 [77995]
    Other proteins in same PDB: d1lixa1, d1lixa3, d1lixb1, d1lixb3, d1lixc1, d1lixc3, d1lixd1, d1lixd3

Details for d1lixa2

PDB Entry: 1lix (more details), 2.87 Å

PDB Description: Human erythrocyte pyruvate kinase: Arg486Trp mutant

SCOP Domain Sequences for d1lixa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1lixa2 c.1.12.1 (A:57-159,A:262-439) Pyruvate kinase, N-terminal domain {Human (Homo sapiens)}
qqqqlpaamadtflehlclldidsepvaarstsiiatigpasrsverlkemikagmniar
lnfshgsheyhaesianvreavesfagsplsyrpvaialdtkgXpglseqdvrdlrfgve
hgvdivfasfvrkasdvaavraalgpeghgikiiskienhegvkrfdeilevsdgimvar
gdlgieipaekvflaqkmmigrcnlagkpvvcatqmlesmitkprptraetsdvanavld
gadcimlsgetakgnfpveavkmqhaiareaeaavyhrqlfe

SCOP Domain Coordinates for d1lixa2:

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Timeline for d1lixa2: