Lineage for d1knua_ (1knu A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2008476Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2008477Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2008478Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2008960Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
  7. 2008961Species Human (Homo sapiens) [TaxId:9606] [48525] (111 PDB entries)
    Uniprot P37231 232-505
  8. 2009068Domain d1knua_: 1knu A: [77457]
    protein/DNA complex; complexed with ypa

Details for d1knua_

PDB Entry: 1knu (more details), 2.5 Å

PDB Description: ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with a synthetic agonist
PDB Compounds: (A:) Peroxisome proliferator activated receptor gamma

SCOPe Domain Sequences for d1knua_:

Sequence, based on SEQRES records: (download)

>d1knua_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkik
fkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvh
eiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsd
laifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlr
qivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records): (download)

>d1knua_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkik
fkhkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmla
slmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiavi
ilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvq
llqvikktetdmslhpllqeiykdl

SCOPe Domain Coordinates for d1knua_:

Click to download the PDB-style file with coordinates for d1knua_.
(The format of our PDB-style files is described here.)

Timeline for d1knua_: