SCOPe 2.08: Domain d1kfca_: 1kfc A:

Lineage for d1kfca_ (1kfc A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)

6. Protein Trp synthase alpha-subunit [51388] (9 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (72 PDB entries)

8. Domain d1kfca_: 1kfc A: [77371]
   Other proteins in same PDB: d1kfcb_
   complexed with ipl, na, plp; mutant

Details for d1kfca_

PDB Entry: 1kfc, 1.5 Å

PDB Description: crystal structure of alphat183v mutant of tryptophan synthase from salmonella typhimurium with indole propanol phosphate

PDB Compounds: (A:) tryptophan synthase alpha chain

SCOPe Domain Sequences for d1kfca_:

Sequence, based on SEQRES records:

>d1kfca_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlaiirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvvgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra

Sequence, based on observed residues (ATOM records):

>d1kfca_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlaiirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllslh
hlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspkqmlae
lrsfvsamkaasra

Timeline for d1kfca_:

• d1kfca_ first appeared in SCOP 1.63
  
• d1kfca_ appears in SCOPe 2.07