Lineage for d1kf9d_ (1kf9 D:)

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 212476Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 212477Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglments of the two crossover connections
  5. 212478Family a.26.1.1: Long-chain cytokines [47267] (9 proteins)
  6. 212503Protein Growth hormone, somatotropin [47276] (1 species)
  7. 212504Species Human (Homo sapiens) [TaxId:9606] [47277] (9 PDB entries)
  8. 212511Domain d1kf9d_: 1kf9 D: [77356]
    Other proteins in same PDB: d1kf9b1, d1kf9b2, d1kf9c1, d1kf9c2, d1kf9e1, d1kf9e2, d1kf9f1, d1kf9f2
    phage display derived variant

Details for d1kf9d_

PDB Entry: 1kf9 (more details), 2.6 Å

PDB Description: phage display derived variant of human growth hormone complexed with two copies of the extracellular domain of its receptor

SCOP Domain Sequences for d1kf9d_:

Sequence, based on SEQRES records: (download)

>d1kf9d_ a.26.1.1 (D:) Growth hormone, somatotropin {Human (Homo sapiens)}
fptiplsrladnawlradrlnqlafdtyqefeeayipkeqihsfwwnpqtslcpsesipt
psnkeetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
iqtlmgrledgsprtgqifkqtyskfdtnshnddallknygllycfnkdmskvstylrtv
qcrsvegscg

Sequence, based on observed residues (ATOM records): (download)

>d1kf9d_ a.26.1.1 (D:) Growth hormone, somatotropin {Human (Homo sapiens)}
fptiplsrladnawlradrlnqlafdtyqefeeayipkeqihsfwwtslcpsesiptpsn
keetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleegiqt
lmgrlllknygllycfnkdmskvstylrtvqcrsvscg

SCOP Domain Coordinates for d1kf9d_:

Click to download the PDB-style file with coordinates for d1kf9d_.
(The format of our PDB-style files is described here.)

Timeline for d1kf9d_: