SCOPe 2.05: Domain d1k6ma2: 1k6m A:252-470

Lineage for d1k6ma2 (1k6m A:252-470)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.60: Phosphoglycerate mutase-like [53253] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 324156; strand 5 is antiparallel to the rest

4. Superfamily c.60.1: Phosphoglycerate mutase-like [53254] (4 families)

5. Family c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53267] (1 protein)

6. Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53268] (2 species)
   bifunctional enzyme

7. Species Human (Homo sapiens) [TaxId:9606] [82454] (1 PDB entry)

8. Domain d1k6ma2: 1k6m A:252-470 [77276]
   Other proteins in same PDB: d1k6ma1, d1k6mb1
   complexed with ags, po4

Details for d1k6ma2

PDB Entry: 1k6m, 2.4 Å

PDB Description: crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase

PDB Compounds: (A:) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-phosphatase

SCOPe Domain Sequences for d1k6ma2:

Sequence; same for both SEQRES and ATOM records:

>d1k6ma2 c.60.1.4 (A:252-470) 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain {Human (Homo sapiens) [TaxId: 9606]}
siylcrhgeselnirgriggdsglsvrgkqyayalanfiqsqgisslkvftsrmkrtiqt
aealgvpyeqfkalneidagvceemtyeeiqehypeefalrdqdkyryrypkgesyedlv
qrlepvimelerqenvlvichqavmrcllayfldksseelpylkcplhtvlkltpvaygc
kvesiylnveavnthrekpenvditrepeealdtvpahy

Timeline for d1k6ma2:

• d1k6ma2 first appeared in SCOP 1.63
  
• d1k6ma2 appears in SCOPe 2.04
  
• d1k6ma2 appears in SCOPe 2.06
  
• d1k6ma2 appears in the current release, SCOPe 2.08