SCOPe 2.06: Domain d1k6ma1: 1k6m A:39-251

Lineage for d1k6ma1 (1k6m A:39-251)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52589] (1 protein)
   automatically mapped to Pfam PF01591

6. Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52590] (2 species)
   bifunctional enzyme

7. Species Human (Homo sapiens) [TaxId:9606] [82398] (1 PDB entry)

8. Domain d1k6ma1: 1k6m A:39-251 [77275]
   Other proteins in same PDB: d1k6ma2, d1k6mb2
   complexed with ags, po4

Details for d1k6ma1

PDB Entry: 1k6m, 2.4 Å

PDB Description: crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase

PDB Compounds: (A:) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-phosphatase

SCOPe Domain Sequences for d1k6ma1:

Sequence; same for both SEQRES and ATOM records:

>d1k6ma1 c.37.1.7 (A:39-251) 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain {Human (Homo sapiens) [TaxId: 9606]}
nsptmvimvglpargktyistkltrylnfigtptkvfnlgqyrreavsyknyefflpdnm
ealqirkqcalaalkdvhnylsheeghvavfdatnttrerrslilqfakehgykvffies
icndpgiiaenirqvklgspdyidcdrekvledflkriecyevnyqpldeeldshlsyik
ifdvgtrymvnrvqdhiqsrtvyylmnihvtpr

Timeline for d1k6ma1:

• d1k6ma1 first appeared in SCOP 1.63
  
• d1k6ma1 appears in SCOPe 2.05
  
• d1k6ma1 appears in SCOPe 2.07
  
• d1k6ma1 appears in the current release, SCOPe 2.08