Lineage for d1k4ta3 (1k4t A:201-430)

  1. Root: SCOP 1.65
  2. 338536Class e: Multi-domain proteins (alpha and beta) [56572] (38 folds)
  3. 339611Fold e.15: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56740] (1 superfamily)
    2 domains: alpha+beta and all-beta
  4. 339612Superfamily e.15.1: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56741] (1 family) (S)
  5. 339613Family e.15.1.1: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56742] (1 protein)
  6. 339614Protein Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56743] (2 species)
  7. 339617Species Human (Homo sapiens) [TaxId:9606] [56744] (8 PDB entries)
  8. 339618Domain d1k4ta3: 1k4t A:201-430 [77265]
    Other proteins in same PDB: d1k4ta1, d1k4ta2
    complexed with hg, pg4, ptr, tgp, ttc, ttg

Details for d1k4ta3

PDB Entry: 1k4t (more details), 2.1 Å

PDB Description: human dna topoisomerase i (70 kda) in complex with the poison topotecan and covalent complex with a 22 base pair dna duplex

SCOP Domain Sequences for d1k4ta3:

Sequence; same for both SEQRES and ATOM records: (download)

>d1k4ta3 e.15.1.1 (A:201-430) Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment {Human (Homo sapiens)}
qkwkwweeerypegikwkflehkgpvfappyeplpenvkfyydgkvmklspkaeevatff
akmldheyttkeifrknffkdwrkemtneekniitnlskcdftqmsqyfkaqtearkqms
keeklkikeenekllkeygfcimdnhkerianfkieppglfrgrgnhpkmgmlkrrimpe
diiincskdakvpspppghkwkevrhdnkvtwlvswteniqgsikyimln

SCOP Domain Coordinates for d1k4ta3:

Click to download the PDB-style file with coordinates for d1k4ta3.
(The format of our PDB-style files is described here.)

Timeline for d1k4ta3: