Lineage for d1k4ta1 (1k4t A:641-712)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1979497Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
    2 helices; antiparallel hairpin, left-handed twist
  4. 1979736Superfamily a.2.8: Eukaryotic DNA topoisomerase I, dispensable insert domain [46596] (1 family) (S)
  5. 1979737Family a.2.8.1: Eukaryotic DNA topoisomerase I, dispensable insert domain [46597] (1 protein)
  6. 1979738Protein Eukaryotic DNA topoisomerase I, dispensable insert domain [46598] (1 species)
  7. 1979739Species Human (Homo sapiens) [TaxId:9606] [46599] (9 PDB entries)
    Uniprot P11387 203-767
  8. 1979740Domain d1k4ta1: 1k4t A:641-712 [77263]
    Other proteins in same PDB: d1k4ta2, d1k4ta3
    protein/DNA complex; complexed with hg, pg4, ttc, ttg

Details for d1k4ta1

PDB Entry: 1k4t (more details), 2.1 Å

PDB Description: human dna topoisomerase i (70 kda) in complex with the poison topotecan and covalent complex with a 22 base pair dna duplex
PDB Compounds: (A:) DNA topoisomerase I

SCOPe Domain Sequences for d1k4ta1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1k4ta1 a.2.8.1 (A:641-712) Eukaryotic DNA topoisomerase I, dispensable insert domain {Human (Homo sapiens) [TaxId: 9606]}
eksmmnlqtkidakkeqladarrdlksakadakvmkdaktkkvveskkkavqrleeqlmk
levqatdreenk

SCOPe Domain Coordinates for d1k4ta1:

Click to download the PDB-style file with coordinates for d1k4ta1.
(The format of our PDB-style files is described here.)

Timeline for d1k4ta1: