SCOP 1.67: Domain d1jvab1: 1jva B:279-463,B:699-741

Lineage for d1jvab1 (1jva B:279-463,B:699-741)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
   complex fold made of five beta-hairpin units and a b-ribbon arc

4. Superfamily b.86.1: Hedgehog/intein (Hint) domain [51294] (2 families)
   duplication: contains two intertwined structural repeats

5. Family b.86.1.2: Intein (protein splicing domain) [51298] (4 proteins)

6. Protein VMA1-derived endonuclease (VDE) PI-Scei intein [51299] (1 species)
   also contains a homing endonuclease and DNA-binding domains

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51300] (7 PDB entries)

8. Domain d1jvab1: 1jva B:279-463,B:699-741 [77178]
   Other proteins in same PDB: d1jvaa2, d1jvaa3, d1jvab2, d1jvab3
   contains the N and C extein propeptides
   mutant

Details for d1jvab1

PDB Entry: 1jva, 2.1 Å

PDB Description: crystal structure of the vma1-derived endonuclease bearing the n and c extein propeptides

SCOP Domain Sequences for d1jvab1:

Sequence, based on SEQRES records:

>d1jvab1 b.86.1.2 (B:279-463,B:699-741) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae)}
iiyvgsfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksq
hrahksdssrevpellkftcnatnelvvrtprsvrrlsrtikgveyfevitfemgqkkap
dgrivelvkevsksypisegperanelvesyrkasnkayfewtieardlsllgshvrkat
yqtyaXcrgfyfelqelkeddyygitlsddsdhqfllanqvvvhssger

Sequence, based on observed residues (ATOM records):

>d1jvab1 b.86.1.2 (B:279-463,B:699-741) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae)}
iiyvgsfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksp
ellkftcnatnelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgrivelvkevsk
sypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtyaXcrgfyfe
lqelkeddyygitlsddsdhqfllanqvvvhssger

Timeline for d1jvab1:

• d1jvab1 first appeared in SCOP 1.63
  
• d1jvab1 appears in SCOP 1.65
  
• d1jvab1 appears in SCOP 1.69
  
• d1jvab1 appears in the current release, SCOPe 2.08