SCOPe 2.08: Domain d1jvaa1: 1jva A:282-463,A:699-741

Lineage for d1jvaa1 (1jva A:282-463,A:699-741)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
   complex fold made of five beta-hairpin units and a b-ribbon arc

4. Superfamily b.86.1: Hedgehog/intein (Hint) domain [51294] (3 families)
   duplication: contains two intertwined structural repeats

5. Family b.86.1.2: Intein (protein splicing domain) [51298] (5 proteins)

6. Protein VMA1-derived endonuclease (VDE) PI-Scei intein [51299] (1 species)
   also contains a homing endonuclease and DNA-binding domains

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51300] (8 PDB entries)
   Uniprot P17255 284-737

8. Domain d1jvaa1: 1jva A:282-463,A:699-741 [77175]
   Other proteins in same PDB: d1jvaa2, d1jvaa3, d1jvab2, d1jvab3
   contains the N and C extein propeptides

Details for d1jvaa1

PDB Entry: 1jva, 2.1 Å

PDB Description: crystal structure of the vma1-derived endonuclease bearing the n and c extein propeptides

PDB Compounds: (A:) vma1-derived homing endonuclease x10sss

SCOPe Domain Sequences for d1jvaa1:

Sequence, based on SEQRES records:

>d1jvaa1 b.86.1.2 (A:282-463,A:699-741) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vgsfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhra
hksdssrevpellkftcnatnelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgr
ivelvkevsksypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqt
yaXcrgfyfelqelkeddyygitlsddsdhqfllanqvvvhssger

Sequence, based on observed residues (ATOM records):

>d1jvaa1 b.86.1.2 (A:282-463,A:699-741) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vgsfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksevpe
llkftcnatnelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgrivelvkevsks
ypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtyaXcrgfyfel
qelkeddyygitlsddsdhqfllanqvvvhssger

Timeline for d1jvaa1:

• d1jvaa1 first appeared in SCOP 1.63
  
• d1jvaa1 appears in SCOPe 2.07