Lineage for d1izia_ (1izi A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2058816Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2058832Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2059066Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (466 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 2059766Domain d1izia_: 1izi A: [76990]
    complexed with cl, q50; mutant

Details for d1izia_

PDB Entry: 1izi (more details), 2.15 Å

PDB Description: Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants
PDB Compounds: (A:) proteinase

SCOPe Domain Sequences for d1izia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1izia_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}

SCOPe Domain Coordinates for d1izia_:

Click to download the PDB-style file with coordinates for d1izia_.
(The format of our PDB-style files is described here.)

Timeline for d1izia_: