SCOP 1.63: Domain d1iz2a_: 1iz2 A:

Lineage for d1iz2a_ (1iz2 A:)

1. Root: SCOP 1.63

2. Class e: Multi-domain proteins (alpha and beta) [56572] (39 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (1 family)

5. Family e.1.1.1: Serpins [56575] (14 proteins)

6. Protein Antitrypsin, alpha-1 [56582] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56583] (12 PDB entries)

8. Domain d1iz2a_: 1iz2 A: [76975]
   intact chain
   complexed with sum; mutant

Details for d1iz2a_

PDB Entry: 1iz2, 2.2 Å

PDB Description: interactions causing the kinetic trap in serpin protein folding

SCOP Domain Sequences for d1iz2a_:

Sequence; same for both SEQRES and ATOM records:

>d1iz2a_ e.1.1.1 (A:) Antitrypsin, alpha-1 {Human (Homo sapiens)}
nkitpnlaefafslyrqlahqsnstnilfspvsiaaafamlslgakgdthdeileglnfn
lteipeaqihegfqellhtlnqpdsqlqlttgnglflseglklvdkfledvkklyhseaf
tvnfgdteeakkqindyvekgtqgkivdlvkeldrdtvfalvnyiffkgkwerpfevkdt
eeedfhvdqvttvkvpmmkrlgmfniqhckklsswvllmkylgnataifflpdegklqhl
enelthdiitkflenedrrsaslhlpklsitgtydlksvlgqlgitkvfsngadlsgvte
eaplklskavhkavltidekgteaagamfleaipmsippeakfnkpfvfliidqntkapl
fmgrvvnptqk

Timeline for d1iz2a_:

• d1iz2a_ is new in SCOP 1.63
  
• d1iz2a_ appears in SCOP 1.65
  
• d1iz2a_ appears in the current release, SCOPe 2.08