Lineage for d1it9l2 (1it9 L:112-214)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2020524Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 protein domains)
  6. 2023413Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 2023414Species Human (Homo sapiens) [TaxId:9606] [88569] (144 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 2023586Domain d1it9l2: 1it9 L:112-214 [76786]
    Other proteins in same PDB: d1it9h1, d1it9h2, d1it9l1
    part of humanized anti-human Fas Fab HFE7A

Details for d1it9l2

PDB Entry: 1it9 (more details), 2.8 Å

PDB Description: crystal structure of an antigen-binding fragment from a humanized version of the anti-human fas antibody hfe7a
PDB Compounds: (L:) humanized antibody hfe7a, light chain

SCOPe Domain Sequences for d1it9l2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1it9l2 b.1.1.2 (L:112-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1it9l2:

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Timeline for d1it9l2:

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