SCOP 1.63: Domain d1h3ia2: 1h3i A:194-344

Lineage for d1h3ia2 (1h3i A:194-344)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.85: beta-clip [51268] (7 superfamilies)
   double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll

4. Superfamily b.85.7: SET domain [82199] (3 families)
   duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
   also contains a substrate-binding alpha+beta subdomain inserted in the core

5. Family b.85.7.1: Histone lysine methyltransferases [82200] (3 proteins)
   contains metal-binding preSET and postSET domains

6. Protein Histone H3 K4-specific methyltransferase SET7/9 catalytic domain [82205] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82206] (6 PDB entries)

8. Domain d1h3ia2: 1h3i A:194-344 [76636]
   Other proteins in same PDB: d1h3ia1, d1h3ib1

Details for d1h3ia2

PDB Entry: 1h3i, 2.1 Å

PDB Description: crystal structure of the histone methyltransferase set7/9

SCOP Domain Sequences for d1h3ia2:

Sequence; same for both SEQRES and ATOM records:

>d1h3ia2 b.85.7.1 (A:194-344) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens)}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygydhsppgk

Timeline for d1h3ia2:

• d1h3ia2 is new in SCOP 1.63
  
• d1h3ia2 appears in SCOP 1.65
  
• d1h3ia2 appears in the current release, SCOPe 2.08