Class b: All beta proteins [48724] (177 folds) |
Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies) one turn of helix is made by two pairs of antiparallel strands linked with short turns has appearance of a sandwich of distinct architecture and jelly-roll topology |
Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold |
Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein) |
Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [82196] (34 PDB entries) |
Domain d1h2la_: 1h2l A: [76574] Other proteins in same PDB: d1h2ls_ complex with HIF-1 alpha fragment peptide complexed with akg, fe2, so4 |
PDB Entry: 1h2l (more details), 2.25 Å
SCOPe Domain Sequences for d1h2la_:
Sequence, based on SEQRES records: (download)
>d1h2la_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]} epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahq kvaimrniekmlgealgnpqevgpllntmikgryn
>d1h2la_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]} epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpeyplkahqkva imrniekmlgealgnpqevgpllntmikgryn
Timeline for d1h2la_: