SCOPe 2.08: Domain d1h26a1: 1h26 A:1-297

Lineage for d1h26a1 (1h26 A:1-297)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
   Uniprot P24941

8. Domain d1h26a1: 1h26 A:1-297 [76528]
   Other proteins in same PDB: d1h26a2, d1h26b1, d1h26b2, d1h26c2, d1h26d1, d1h26d2
   complex with cyclin and an 11-residue recruitment peptide from p53

Details for d1h26a1

PDB Entry: 1h26, 2.24 Å

PDB Description: cdk2/cyclin a in complex with an 11-residue recruitment peptide from p53

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d1h26a1:

Sequence; same for both SEQRES and ATOM records:

>d1h26a1 d.144.1.7 (A:1-297) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr

Timeline for d1h26a1:

• d1h26a1 first appeared in SCOP 1.63, called d1h26a_
  
• d1h26a1 appears in SCOPe 2.07