Lineage for d1h25c_ (1h25 C:)

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 262793Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 262794Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 262795Family d.144.1.1: Serine/threonin kinases [56113] (21 proteins)
  6. 262839Protein Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)
  7. 262840Species Human (Homo sapiens) [TaxId:9606] [56115] (47 PDB entries)
  8. 262889Domain d1h25c_: 1h25 C: [76525]
    Other proteins in same PDB: d1h25b1, d1h25b2, d1h25d1, d1h25d2
    complex with cyclin and an 11-residue recruitment peptide from retinoblastoma-associated protein
    complexed with tpo

Details for d1h25c_

PDB Entry: 1h25 (more details), 2.5 Å

PDB Description: cdk2/cyclin a in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein

SCOP Domain Sequences for d1h25c_:

Sequence, based on SEQRES records: (download)

>d1h25c_ d.144.1.1 (C:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv

Sequence, based on observed residues (ATOM records): (download)

>d1h25c_ d.144.1.1 (C:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdvvpp
ldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv

SCOP Domain Coordinates for d1h25c_:

Click to download the PDB-style file with coordinates for d1h25c_.
(The format of our PDB-style files is described here.)

Timeline for d1h25c_: