Lineage for d1h25c1 (1h25 C:1-293)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (401 PDB entries)
    Uniprot P24941
  8. 2543337Domain d1h25c1: 1h25 C:1-293 [76525]
    Other proteins in same PDB: d1h25a2, d1h25b1, d1h25b2, d1h25c2, d1h25d1, d1h25d2
    complex with cyclin and an 11-residue recruitment peptide from retinoblastoma-associated protein

Details for d1h25c1

PDB Entry: 1h25 (more details), 2.5 Å

PDB Description: cdk2/cyclin a in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein
PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d1h25c1:

Sequence, based on SEQRES records: (download)

>d1h25c1 d.144.1.7 (C:1-293) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv

Sequence, based on observed residues (ATOM records): (download)

>d1h25c1 d.144.1.7 (C:1-293) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdvvppl
dedgrsllsqmlhydpnkrisakaalahpffqdvtkpv

SCOPe Domain Coordinates for d1h25c1:

Click to download the PDB-style file with coordinates for d1h25c1.
(The format of our PDB-style files is described here.)

Timeline for d1h25c1: