Lineage for d1gs4a_ (1gs4 A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2008476Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2008477Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2008478Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2008479Protein Androgen receptor [63621] (4 species)
  7. 2008489Species Human (Homo sapiens) [TaxId:9606] [63623] (62 PDB entries)
    Uniprot P10275 671-919
  8. 2008515Domain d1gs4a_: 1gs4 A: [76328]
    complexed with po4, zk5; mutant

Details for d1gs4a_

PDB Entry: 1gs4 (more details), 1.95 Å

PDB Description: structural basis for the glucocorticoid response in a mutant human androgen receptor (arccr) derived from an androgen-independent prostate cancer
PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d1gs4a_:

Sequence, based on SEQRES records: (download)

>d1gs4a_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
qpiflnvleaiepgvvcaghdnnqpdsfaalhsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknp
tscsrrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfh

Sequence, based on observed residues (ATOM records): (download)

>d1gs4a_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
qpiflnvleaiepgvvcaghdnnqpdsfaalhsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrscs
rrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgkvkp
iyfh

SCOPe Domain Coordinates for d1gs4a_:

Click to download the PDB-style file with coordinates for d1gs4a_.
(The format of our PDB-style files is described here.)

Timeline for d1gs4a_: