Lineage for Superfamily c.116.1: alpha/beta knot

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 404674Fold c.116: alpha/beta knot [75216] (1 superfamily)
    core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot
  4. 404675Superfamily c.116.1: alpha/beta knot [75217] (5 families) (S)
    known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
    all known members have dimeric structures

Families:

  1. 404676c.116.1.1: SpoU-like RNA 2'-O ribose methyltransferase [75218] (4 proteins)
    contains extra strand (3) in the parallel beta-sheet, order 321546
  2. 404697c.116.1.2: Hypothetical protein MTH1 (MT0001), dimerisation domain [75221] (1 protein)
    contains extra strand (3) in the parallel beta-sheet, order 321546; interrupted by an insert OB-fold domain
  3. 404702c.116.1.3: YbeA-like [82371] (3 proteins)
  4. 404718c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (1 protein)
    fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain
  5. 404729c.116.1.5: YggJ C-terminal domain-like [89632] (2 proteins)
    contains extra strand (3) in the parallel beta-sheet, order 321546; similar dimerisation to the MTH1 domain

More info for Superfamily c.116.1: alpha/beta knot

Timeline for Superfamily c.116.1: alpha/beta knot: