Lineage for Superfamily c.116.1: alpha/beta knot

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2150174Fold c.116: alpha/beta knot [75216] (1 superfamily)
    core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot
  4. 2150175Superfamily c.116.1: alpha/beta knot [75217] (9 families) (S)
    known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
    all known members have dimeric structures

Families:

  1. 2150176c.116.1.1: SpoU-like RNA 2'-O ribose methyltransferase [75218] (5 protein domains)
    contains extra strand (3) in the parallel beta-sheet, order 321546
  2. 2150204c.116.1.2: Hypothetical protein MTH1 (MT0001), dimerisation domain [75221] (1 protein)
    contains extra strand (3) in the parallel beta-sheet, order 321546; interrupted by an insert OB-fold domain
  3. 2150209c.116.1.3: YbeA-like [82371] (5 protein domains)
    Pfam PF02590
  4. 2150238c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 protein domains)
    fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain
  5. 2150262c.116.1.5: YggJ C-terminal domain-like [89632] (4 protein domains)
    contains extra strand (3) in the parallel beta-sheet, order 321546; similar dimerisation to the MTH1 domain
  6. 2150286c.116.1.6: EMG1/NEP1-like [159513] (3 protein domains)
    Pfam PF03587; structurally most similar to the AF1056-like family, but more decorated
  7. 2150303c.116.1.7: AF1056-like [159518] (2 protein domains)
    Pfam PF04013; DUF358
  8. 2150312c.116.1.8: AF0751-like [159523] (1 protein)
    Pfam PF01994; DUF127
  9. 2150317c.116.1.0: automated matches [191557] (1 protein)
    not a true family

More info for Superfamily c.116.1: alpha/beta knot

Timeline for Superfamily c.116.1: alpha/beta knot: