Lineage for Protein: Decameric fructose-6-phosphate aldolase/transaldolase

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 681098Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 683918Superfamily c.1.10: Aldolase [51569] (8 families) (S)
    Common fold covers whole protein structure
  5. 683919Family c.1.10.1: Class I aldolase [51570] (12 proteins)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  6. 683990Protein Decameric fructose-6-phosphate aldolase/transaldolase [75085] (3 species)
    forms helix-swapped pentamers

Species:

  1. 683991Escherichia coli [TaxId:562] [75086] (1 PDB entry)
  2. 684002Thermotoga maritima [TaxId:2336] [117379] (1 PDB entry)
  3. 684023Thermus thermophilus [TaxId:274] [141836] (1 PDB entry)
    clear orthologue of the E.coli protein; annotated as transaldolase in UniProt

More info for Protein Decameric fructose-6-phosphate aldolase/transaldolase from c.1.10.1: Class I aldolase

Timeline for Protein Decameric fructose-6-phosphate aldolase/transaldolase from c.1.10.1: Class I aldolase: