SCOPe 2.08: Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain

Lineage for Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins)
   automatically mapped to Pfam PF13147

Proteins:

1. D-hydantoinase [75074] (4 species)

   1. Species Bacillus sp. AR9 [TaxId:301298] [141802] (1 PDB entry)
      Uniprot Q5DLU2 2-460

   2. Species Bacillus stearothermophilus [TaxId:1422] [75076] (1 PDB entry)

   3. Species Burkholderia pickettii [TaxId:329] [89488] (1 PDB entry)

   4. Species Thermus sp. [TaxId:275] [75075] (2 PDB entries)

2. Dihydropyrimidinase related protein-1 [102084] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [102085] (1 PDB entry)

3. Dihydropyrimidine amidohydrolase Pyd2 [141805] (2 species)

   1. Species Slime mold (Dictyostelium discoideum) [TaxId:44689] [141807] (1 PDB entry)
      Uniprot Q86LT2 60-393

   2. Species Yeast (Saccharomyces kluyveri) [TaxId:4934] [141806] (3 PDB entries)
      Uniprot Q9P903 57-440

4. L-hydantoinase [75077] (1 species)

   • Species Arthrobacter aurescens [TaxId:43663] [75078] (1 PDB entry)

5. Two-domain dihydroorotase [141803] (1 species)

   • Species Aquifex aeolicus [TaxId:63363] [141804] (2 PDB entries)
     Uniprot O66990 56-365

More info for Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain

Timeline for Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain:

• Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain first appeared in SCOP 1.61
  
• Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain appears in SCOPe 2.07